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rabbit anti spp1 primary antibody  (Proteintech)


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    Proteintech rabbit anti spp1 primary antibody
    (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of <t>Spp1,</t> Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.
    Rabbit Anti Spp1 Primary Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 523 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti spp1 primary antibody/product/Proteintech
    Average 96 stars, based on 523 article reviews
    rabbit anti spp1 primary antibody - by Bioz Stars, 2026-03
    96/100 stars

    Images

    1) Product Images from "The Old Genetically Heterogeneous Mouse Model Recapitulates Chronic and Persistent Idiopathic Pulmonary Fibrosis with Strong Senescence Signatures"

    Article Title: The Old Genetically Heterogeneous Mouse Model Recapitulates Chronic and Persistent Idiopathic Pulmonary Fibrosis with Strong Senescence Signatures

    Journal: bioRxiv

    doi: 10.1101/2025.07.22.665978

    (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of Spp1, Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.
    Figure Legend Snippet: (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of Spp1, Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.

    Techniques Used: Gene Expression, Control, Staining, Biomarker Discovery, Expressing



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    rabbit anti spp1 primary antibody  (Proteintech)
    96
    Proteintech rabbit anti spp1 primary antibody
    (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of <t>Spp1,</t> Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.
    Rabbit Anti Spp1 Primary Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti spp1 primary antibody/product/Proteintech
    Average 96 stars, based on 1 article reviews
    rabbit anti spp1 primary antibody - by Bioz Stars, 2026-03
    96/100 stars
    		  Buy from Supplier
    rabbit anti-spp1 polyclonal primary antibody ab10910  (Millipore)
    90
    Millipore rabbit anti-spp1 polyclonal primary antibody ab10910
    (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of <t>Spp1,</t> Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.
    Rabbit Anti Spp1 Polyclonal Primary Antibody Ab10910, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti-spp1 polyclonal primary antibody ab10910/product/Millipore
    Average 90 stars, based on 1 article reviews
    rabbit anti-spp1 polyclonal primary antibody ab10910 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of Spp1, Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.

    Journal: bioRxiv

    Article Title: The Old Genetically Heterogeneous Mouse Model Recapitulates Chronic and Persistent Idiopathic Pulmonary Fibrosis with Strong Senescence Signatures

    doi: 10.1101/2025.07.22.665978

    Figure Lengend Snippet: (A) Senescent genes identified among the DEGs at D24 from the SEN MAYO panel. (A-i) Leading edge genes identified in the SEN MAYO panel at D72. (B) Venn diagram indicating an overlap of DEGs between C57BL/6J and HET3 mice using the SEN MAYO senescence gene set. 11 genes from the SEN MAYO panel were found to be present in both sets. C57BL/6J data re-analyzed from . (B-i) Venn diagram comparing genes from Bleomycin-treated mice at D24 and D72 (3.5 mg/kg) with SEN MAYO senescence gene panel and Human IPF data. Data was re-analyzed from . (C, C-i) Gene expression of Spp1, Igf1 and Il6 of sham and bleomycin-treated mice. Rpl13a was used as housekeeping control. Significance calculated using unpaired t-test; data represented as mean ± SEM at D24 and D72. (D) Representative IHC images at D24 and D72 of sham and bleomycin-treated mice stained for SPP1. Scale bar = 50 um. (D-i) Spp1 positive cell quantification at D24 and (D-ii) D72. Data represented as mean of four different fields of view per mouse ± SEM, unpaired t-test, *p ≤ 0.05, ** p ≤ 0.002, ns ≥ 0.05. (E) Validation of Spp1 expression data via spatial transcriptomic analysis in mouse IPF samples. Mouse samples with IPF showcase higher expression of Spp1. (E-i) Validation of SPP1 expression in human IPF samples. Data was re-analyzed from Franzen et al., 2024 for both human and mouse tissues. IPF = Freshly frozen tissue. IPF lung tissue collected with severe tissue remodeling. Control = Healthy lung tissue no known evidence of lung disease.

    Article Snippet: Rabbit anti-Spp1 primary antibody (Proteintech, cat no. 22952-1-AP) was used at a 1:300 dilution overnight at 4°C.

    Techniques: Gene Expression, Control, Staining, Biomarker Discovery, Expressing